AOD-9604
AODModified GH fragment studied in lipolysis research.
Also known as: Anti-Obesity Drug 9604, HGH Fragment 176-191 analog
Overview
AOD-9604 is a modified fragment of the C-terminus of growth hormone studied in fat-metabolism and lipolysis research without the growth-promoting effects of full GH.
A modified fragment of the C-terminus of human growth hormone studied for its lipolytic (fat-mobilizing) effects without the glucose-raising or growth-promoting actions of full-length GH. Research reports stimulation of fat breakdown and inhibition of lipogenesis in adipose models.
Derived from the 176-191 region of growth hormone; studied for stimulating lipolysis and inhibiting lipogenesis without affecting blood glucose or IGF-1.
Molecular information
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-PheAdds an N-terminal tyrosine to the natural hGH 177-191 fat-reducing region.
Pharmacokinetics
Illustrative relative-concentration model derived from published pharmacokinetic research. Curve is normalized and provided for educational comparison only — not a dosing schedule.
Research applications
- Lipolysis and fat-metabolism research
- Body-composition studies
- Metabolic-signaling investigations
Research protocols
Protocols summarized from published research models. Provided for scientific reference only — not dosing guidance for human use.
Observed effects timeline
Aggregated observations reported across research literature. Timing and magnitude vary by model and are not a guarantee of outcome.
Week 1–2
Onset of lipolytic signaling reported in adipose-research models.
Week 4–12
Reported changes in fat metabolism without significant IGF-1 elevation.
Research compatibility
Describes how compounds are studied alongside one another in the literature. Not a recommendation to co-administer.
MOTS-c
Complementary metabolic pathways in research.
Tesamorelin
Distinct GH-axis vs. fragment mechanisms.
L-Carnitine
Co-studied in fat-metabolism contexts.
How to reconstitute
Reconstitute with bacteriostatic water, swirl gently, and refrigerate. Avoid shaking to preserve the peptide.
- 1Allow the vial to reach room temperature (15–20 minutes).
- 2Swab the stopper with alcohol and let it air dry.
- 3Add bacteriostatic water slowly down the vial wall.
- 4Swirl gently until dissolved into a clear solution.
- 5Refrigerate at 2–8 °C and protect from light.
Quality indicators
Uniform white powder
Lyophilized cake should be white to off-white without discoloration.
Clear solution
Reconstitutes to a clear, colorless, particle-free solution.
Slight clumping
Small clumps that dissolve completely with gentle swirling are acceptable — shipping can cause minor compaction.
Collapsed or melted appearance
Powder that looks collapsed, melted, or stuck to the vial walls may have been exposed to heat in transit.
Cloudy after reconstitution
Persistent cloudiness, particles, or precipitate after gentle mixing can indicate a degraded or contaminated peptide.
Reported observations & safety
Safety signals reported in the research literature. Compiled for scientific awareness — not medical advice.
- Generally reported as well tolerated in studies, without the glucose effects of full-length GH.
- Human efficacy evidence for body-weight endpoints remains limited.
References & further reading
AOD-9604 lipolytic fragment of human growth hormone (review)
Review of the hGH C-terminal fragment's fat-mobilizing actions and its separation from GH's metabolic effects.
View studyTopics
This entry is provided for educational and informational purposes only. It is not medical advice, a dosing protocol, or a claim of therapeutic benefit. Research compounds are supplied strictly for laboratory and research use — not for human or veterinary consumption.
Large body of preclinical and clinical literature.
This compound is part of our educational reference and is not currently stocked. Browse the catalogue for available research-grade peptides.
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