5-Amino-1MQ
5A1MQNNMT inhibitor studied in metabolism.
Also known as: 5-Amino-1-methylquinolinium
Overview
5-Amino-1MQ is a small-molecule NNMT inhibitor studied in fat-metabolism and cellular-energy research.
A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied in adipocyte models for increasing cellular NAD+ and SAM levels, promoting fat-cell metabolism. Research suggests it may shrink adipocytes and support metabolic flexibility.
Inhibits nicotinamide N-methyltransferase (NNMT), studied for increasing cellular NAD+ and modulating adipocyte metabolism.
Molecular information
A methylquinolinium small molecule; not a peptide, hence oral stability.
Pharmacokinetics
Illustrative relative-concentration model derived from published pharmacokinetic research. Curve is normalized and provided for educational comparison only — not a dosing schedule.
Research applications
- Fat-metabolism research
- Cellular-energy studies
- NAD+ pathway investigations
Research protocols
Protocols summarized from published research models. Provided for scientific reference only — not dosing guidance for human use.
Observed effects timeline
Aggregated observations reported across research literature. Timing and magnitude vary by model and are not a guarantee of outcome.
Week 1–4
Reported increases in cellular NAD+ and metabolic markers in adipocyte research.
Week 4–12
Changes in fat-cell metabolism and body composition reported in models.
Research compatibility
Describes how compounds are studied alongside one another in the literature. Not a recommendation to co-administer.
NAD+
Complementary NAD+-supporting mechanisms in research.
MOTS-c
Co-studied in metabolic-enhancement contexts.
SLU-PP-332
Distinct metabolic pathways.
Quality indicators
Consistent oral form
Research material is typically a capsule; verify labeled concentration.
Dry storage
As a stable small molecule, it does not require cold-chain handling.
Slight clumping
Small clumps that dissolve completely with gentle swirling are acceptable — shipping can cause minor compaction.
Collapsed or melted appearance
Powder that looks collapsed, melted, or stuck to the vial walls may have been exposed to heat in transit.
Cloudy after reconstitution
Persistent cloudiness, particles, or precipitate after gentle mixing can indicate a degraded or contaminated peptide.
Reported observations & safety
Safety signals reported in the research literature. Compiled for scientific awareness — not medical advice.
- Generally reported as well tolerated at research amounts; human safety data are limited.
- Most evidence is preclinical or early-stage.
References & further reading
NNMT inhibition and adipose metabolism (preclinical)
Research reporting that NNMT inhibition raises cellular NAD+ and influences adipocyte metabolism.
View studyTopics
This entry is provided for educational and informational purposes only. It is not medical advice, a dosing protocol, or a claim of therapeutic benefit. Research compounds are supplied strictly for laboratory and research use — not for human or veterinary consumption.
Sparse published data; largely preliminary or anecdotal.
This compound is part of our educational reference and is not currently stocked. Browse the catalogue for available research-grade peptides.
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