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Longevity & Anti-Aging
Well Researched

Pinealon

PIN

Tripeptide bioregulator studied in brain aging.

Also known as: Pineal peptide

Research dose range100 mcg daily (research models)
Route studiedSubcutaneous
Study durationShort courses (e.g., ~10–20 days)
Storage2–8 °C reconstituted

Overview

Pinealon is a short peptide bioregulator studied in neuroprotection and brain-aging research, part of the short-peptide bioregulator family.

Key research findings

A short peptide bioregulator (tripeptide) in the Khavinson tradition, studied for brain-tissue-specific signaling, neuroprotection, and circadian regulation. The bioregulator concept proposes it binds DNA regulatory regions to normalize neuronal gene expression.

Mechanism of action

Studied for penetrating cells and modulating gene expression linked to neuronal protection and oxidative-stress resistance.

Molecular information

Weight~339 Da
LengthTripeptide
TypeNeuro-targeted peptide bioregulator
Amino-acid sequenceGlu-Asp-Arg

Part of the short-peptide bioregulator family targeting brain/neuronal tissue.

Pharmacokinetics

Peak: ~1 hourHalf-life: ~Short (minutes to hours)Cleared: ~24 hours
Peak · 1hHalf-life · 5h

Illustrative relative-concentration model derived from published pharmacokinetic research. Curve is normalized and provided for educational comparison only — not a dosing schedule.

Research applications

  • Neuroprotection research
  • Brain-aging studies
  • Peptide-bioregulator investigations

Research protocols

Protocols summarized from published research models. Provided for scientific reference only — not dosing guidance for human use.

Standard referenceAmount: 100 mcgFrequency: Once dailyRoute: Subcutaneous
Course referenceAmount: 100 mcgFrequency: Daily ~10–20 daysRoute: Subcutaneous

Observed effects timeline

Aggregated observations reported across research literature. Timing and magnitude vary by model and are not a guarantee of outcome.

  1. Course (10–20 days)

    Bioregulator protocols emphasize short, repeatable courses rather than continuous use.

  2. Between courses

    Neuroprotective effects are proposed to persist via gene-regulatory normalization.

Research compatibility

Describes how compounds are studied alongside one another in the literature. Not a recommendation to co-administer.

Epitalon

Complementary bioregulators; frequently used in sequence.

Compatible

Cartalax

Different target tissue; complementary in protocols.

Compatible

Cerebrolysin

Complementary neurotrophic mechanism.

Compatible

How to reconstitute

Important

Reconstitute with bacteriostatic water, swirl gently, and refrigerate. Short peptides are sensitive to heat and agitation.

  1. 1Allow the vial to reach room temperature (15–20 minutes).
  2. 2Swab the stopper with alcohol and let it air dry.
  3. 3Add bacteriostatic water slowly down the vial wall.
  4. 4Swirl gently until dissolved into a clear solution.
  5. 5Refrigerate at 2–8 °C and protect from light.
Open reconstitution calculator

Quality indicators

Uniform white powder

Lyophilized cake should be white to off-white without discoloration.

Clear solution

Reconstitutes to a clear, colorless, particle-free solution.

Slight clumping

Small clumps that dissolve completely with gentle swirling are acceptable — shipping can cause minor compaction.

Collapsed or melted appearance

Powder that looks collapsed, melted, or stuck to the vial walls may have been exposed to heat in transit.

Cloudy after reconstitution

Persistent cloudiness, particles, or precipitate after gentle mixing can indicate a degraded or contaminated peptide.

Reported observations & safety

Safety signals reported in the research literature. Compiled for scientific awareness — not medical advice.

  • Generally reported as well tolerated in the bioregulator literature, which is largely from a single research lineage.
  • Independent replication outside the originating group is limited.

References & further reading

Short peptide bioregulators and neuroprotection (review)

Preclinicalbioregulatorsbrain tissue

Review of the Khavinson short-peptide bioregulator concept and proposed neuroprotective gene-regulatory activity.

View study

Topics

bioregulatorneuroprotectionlongevity

This entry is provided for educational and informational purposes only. It is not medical advice, a dosing protocol, or a claim of therapeutic benefit. Research compounds are supplied strictly for laboratory and research use — not for human or veterinary consumption.

Research level
Well Researched

Substantial peer-reviewed research across multiple models.

Quick reference
Dose range100 mcg daily (research models)
RouteSubcutaneous
DurationShort courses (e.g., ~10–20 days)
Storage2–8 °C reconstituted
Half-life~Short (minutes to hours)
Catalogue status

This compound is part of our educational reference and is not currently stocked. Browse the catalogue for available research-grade peptides.

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