Selank
SELAnxiolytic heptapeptide.
Also known as: TP-7
Overview
Selank is a synthetic heptapeptide studied in anxiety, immune-modulation, and neuropeptide research, derived from the natural peptide tuftsin.
A synthetic analog of the immunomodulatory peptide tuftsin, developed in Russia as an anxiolytic nootropic. Research reports anti-anxiety effects comparable to benzodiazepines but without sedation or dependence, alongside BDNF modulation and immune effects.
Studied for modulating GABAergic and serotonergic signaling and stabilizing enkephalins, supporting anxiolytic-like activity.
Molecular information
Thr-Lys-Pro-Arg-Pro-Gly-ProA Pro-Gly-Pro extension stabilizes the tuftsin fragment against rapid degradation.
Pharmacokinetics
Illustrative relative-concentration model derived from published pharmacokinetic research. Curve is normalized and provided for educational comparison only — not a dosing schedule.
Research applications
- Anxiolytic research
- Immune-modulation studies
- Neuropeptide investigations
Research protocols
Protocols summarized from published research models. Provided for scientific reference only — not dosing guidance for human use.
Observed effects timeline
Aggregated observations reported across research literature. Timing and magnitude vary by model and are not a guarantee of outcome.
Acute
Calming/anxiolytic effects reported within ~30 minutes without sedation.
Week 1–4
Mood and stress-resilience changes reported with continued use.
Research compatibility
Describes how compounds are studied alongside one another in the literature. Not a recommendation to co-administer.
Semax
Classic pairing — focus (Semax) plus calm (Selank).
Adalank
Stabilized Selank analog — redundant.
Bromantane
Complementary energy/anxiolytic pathways.
BPC-157
No known interactions, complementary mechanisms for stress response and neural protection
How to reconstitute
Reconstitute with bacteriostatic water, swirl gently, and refrigerate. Many protocols prepare a metered intranasal spray.
- 1Allow the vial to reach room temperature (15–20 minutes).
- 2Swab the stopper with alcohol and let it air dry.
- 3Add bacteriostatic water slowly down the vial wall.
- 4Swirl gently until dissolved into a clear solution.
- 5Refrigerate at 2–8 °C and protect from light.
Quality indicators
Uniform white powder
Lyophilized cake should be white to off-white without discoloration.
Clear solution
Reconstitutes to a clear, colorless, particle-free solution.
Cold-chain integrity
Reconstituted solution requires 2–8 °C storage.
Slight clumping
Small clumps that dissolve completely with gentle swirling are acceptable — shipping can cause minor compaction.
Collapsed or melted appearance
Powder that looks collapsed, melted, or stuck to the vial walls may have been exposed to heat in transit.
Cloudy after reconstitution
Persistent cloudiness, particles, or precipitate after gentle mixing can indicate a degraded or contaminated peptide.
Reported observations & safety
Safety signals reported in the research literature. Compiled for scientific awareness — not medical advice.
- Generally reported as well tolerated; nasal irritation is the most common intranasal signal.
- Most clinical evidence originates from Russian research and is less replicated elsewhere.
References & further reading
Selank: anxiolytic tuftsin analog (review)
Review of Selank's anti-anxiety and BDNF-modulating effects without the sedation of benzodiazepines.
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This entry is provided for educational and informational purposes only. It is not medical advice, a dosing protocol, or a claim of therapeutic benefit. Research compounds are supplied strictly for laboratory and research use — not for human or veterinary consumption.
Substantial peer-reviewed research across multiple models.
Selank is stocked as a research-grade compound, ≥99% by HPLC, third-party verified.
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